Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.31 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464831 | 1.00 | ESR1 (0.35) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL6601795 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL15372850 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL6601791 | 0.83 | ALDH1A1 (0.43) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL7460002 | 0.78 | LTA4H (0.46) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL7453025 | 0.75 | GAA (0.40) | ESR1ESR2NPC1RAB9AHPGD | |
| SCHEMBL7469592 | 0.75 | GAA (0.40) | ESR1ESR2NPC1RAB9AHPGD | |
| SCHEMBL7453029 | 0.75 | GAA (0.40) | ESR1ESR2NPC1RAB9AHPGD | |
| SCHEMBL7459162 | 0.73 | PKM (0.40) | ESR1ESR2NPC1RAB9AALDH1A1 | |
| SCHEMBL7459160 | 0.73 | PKM (0.40) | ESR1ESR2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184382-A1 | OXIME DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PESTICIDES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-03-06 | — | — | EP | disclosed |