SCHEMBL7469592

SCHEMBL7469592

Cc1nccnc1/C(=N/O)c1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
PKM P14618 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
LTA4H P09960 1/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
POLB P06746 1/20 0.33
TYMP P19971 1/20 0.33
AGTR1 P30556 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
DRD4 P21917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7453029 1.00 GAA (0.40) GAANPC1RAB9APKML3MBTL1
SCHEMBL7453025 1.00 GAA (0.40) GAANPC1RAB9APKML3MBTL1
SCHEMBL7456639 0.77 LTA4H (0.52) NPC1RAB9ALTA4HKMT2AMEN1
SCHEMBL7459162 0.75 PKM (0.40) GAANPC1RAB9APKML3MBTL1
SCHEMBL7459160 0.75 PKM (0.40) GAANPC1RAB9APKML3MBTL1
SCHEMBL7464834 0.75 ESR1 (0.35) GAANPC1RAB9AL3MBTL1ESR1
SCHEMBL7464831 0.75 ESR1 (0.35) GAANPC1RAB9AL3MBTL1ESR1
SCHEMBL11523488 0.74 ESR1 (0.50) NPC1RAB9AESR1ESR2LTA4H
SCHEMBL14831195 0.70 CYP17A1 (0.46)
SCHEMBL14831196 0.70 CYP17A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1184382-A1 OXIME DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PESTICIDES DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-03-06 EP disclosed