Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453894 | 0.89 | HPGD (0.61) | HTR1AADRA1A | |
| Methane SCHEMBL7459255 | 0.84 | HTR1A (0.57) | HTR1AADRA1A | |
| SCHEMBL19971721 | 0.83 | HTR1A (0.58) | HTR1AADRA1A | |
| SCHEMBL7523146 | 0.83 | ALDH1A1 (0.55) | HTR1A | |
| SCHEMBL6983237 | 0.82 | HTR1A (0.63) | HTR1AADRA1A | |
| SCHEMBL6981877 | 0.81 | HTR1A (0.62) | HTR1AADRA1A | |
| SCHEMBL6985467 | 0.80 | HTR1A (0.55) | HTR1AADRA1A | |
| SCHEMBL2075037 | 0.80 | HPGD (0.68) | HTR1A | |
| SCHEMBL2653348 | 0.80 | HPGD (0.73) | HTR1A | |
| SCHEMBL19984097 | 0.80 | HTR1A (0.53) | HTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1160348-C | Aryl-{4-fluoro-4-[(2-pyridin-2-YL-ethylamino)-methyl]-piperidin-1-yl}-methanone derivatives as 5-HT1 receptor antagonists | Ƥ����������ҩƷ��˾ | 2004-08-04 | — | — | CN | disclosed |
| EP-1119564-B1 | ARYL- 4-FLUORO-4- (2-PYRIDIN-2-YL-ETHYLAMINO)-METHYL]-PIPERIDIN-1-YL -METHANONE DERIVATIVES AS 5-HT1 RECEPTOR ANTAGONISTS | PF MEDICAMENT (FR) | 2002-12-18 | — | — | EP | disclosed |
| US-6448268-B1 | TREATING PATHOLOGIES INVOLVING SEROTONINERGIC DYSFUNCTION, IN PARTICULAR ANXIETY, DEPRESSION, NEURODEGENERATION AND THE PERCEPTION OF PAIN; SELECTIVITY; SIDE EFFECT REDUCTION | PIERRE FABRE MEDICAMENT (FR) | 2002-09-10 | — | — | US | disclosed |
| CN-1325396-A | Aryl-{4-fluoro-4-[(2-pyridin-2-YL-ethylamino)-methyl]-piperidin-1-yl}-methanone derivatives as 5-HT1 receptor antagonists | PF MEDICAMENT (FR) | 2001-12-05 | — | — | CN | disclosed |
| EP-1119564-A1 | ARYL- 4-FLUORO-4- (2-PYRIDIN-2-YL-ETHYLAMINO)-METHYL]-PIPERIDIN-1-YL -METHANONE DERIVATIVES AS 5-HT1 RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021953-A1 | ARYL-{4-FLUORO-4-[(2-PYRIDIN-2-YL-ETHYLAMINO)-METHYL]-PIPERIDIN-1-YL}-METHANONE DERIVATIVES AS 5-HT1 RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 2000-04-20 | — | — | WO | disclosed |