Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 10/20 | 0.50 |
| ▸ | GABRD | O14764 | 10/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 10/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.50 |
| ▸ | GABRE | P78334 | 10/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318178 | 0.87 | TNKS (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7461187 | 0.80 | KDM4E (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5206777 | 0.77 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29120190 | 0.73 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29627450 | 0.72 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28739800 | 0.72 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9752059 | 0.72 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2318176 | 0.72 | ALDH1A1 (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5972188 | 0.72 | KMT2A (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL30224994 | 0.71 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739892-B1 | Chromone derivatives | NOVARTIS AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| EP-0739892-A2 | Chromone derivatives | CIBA-GEIGY AG (CH) | 1996-10-30 | — | — | EP | disclosed |