Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460535 | 0.92 | CSNK2A1 (0.35) | PRSS1METAP2ALDH1A1CSNK2A1KDM4E | |
| SCHEMBL7461915 | 0.83 | PTGER4 (0.43) | METAP2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7459480 | 0.82 | CSNK2A1 (0.31) | CSNK2A1RET | |
| SCHEMBL7465711 | 0.80 | ALDH1A1 (0.45) | METAP2ALDH1A1CSNK2A1KDM4EMAPT | |
| SCHEMBL7451372 | 0.79 | PDE3B (0.33) | CSNK2A1RET | |
| SCHEMBL7805962 | 0.76 | PDE4B (0.40) | CYP19A1NUDT1ALDH1A1KDM4EGAA | |
| SCHEMBL7467328 | 0.76 | ALDH1A1 (0.39) | NUDT1METAP2ALDH1A1CSNK2A1HPGD | |
| SCHEMBL7460878 | 0.76 | IMPDH2 (0.41) | PRSS1CYP19A1ALDH1A1 | |
| SCHEMBL7466682 | 0.76 | PRSS1 (0.35) | PRSS1CYP19A1NUDT1ALDH1A1 | |
| SCHEMBL7459989 | 0.75 | RET (0.36) | ALDH1A1CSNK2A1TSHRHSD17B10RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963982-B1 | New diaminobenzene derivatives and these componends containing colouring agents | WELLA AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6132475-A | FOR OXIDATION DYEING OF KERATIN FIBERS; INCLUDES COUPLER AND DEVELOPER, IN WHICH THE DEVELOPER IS A SUBSTITUTED 2-(FURYL, THIENYL, PYRROLYL, OR SELENOPHENE) P-DIAMINOBENZENE DERIVATIVE OF GIVEN FORMULA; COLORFASTNESS, WASHFASTNESS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |
| EP-0963982-A2 | New diaminobenzene derivatives and these componends containing colouring agents | Wella Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |