Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254281 | 0.86 | GAA (0.48) | GAAEPHX2 | |
| SCHEMBL7256256 | 0.74 | AKT1 (0.34) | AKT1AKT2 | |
| SCHEMBL21233040 | 0.70 | KDM4E (0.39) | GAA | |
| SCHEMBL277590 | 0.68 | — | — | |
| SCHEMBL511015 | 0.66 | ALDH1A1 (0.38) | — | |
| SCHEMBL70574 | 0.66 | L3MBTL1 (0.44) | AKT1AKT2 | |
| SCHEMBL8313319 | 0.66 | KCNN4 (0.36) | — | |
| SCHEMBL27743631 | 0.66 | MAPT (0.37) | — | |
| SCHEMBL69872 | 0.66 | KCNN4 (0.36) | — | |
| SCHEMBL18229954 | 0.66 | KCNN4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036064-A4 | SELECTIVE BETA 3-ADRENERGIC AGONISTS | LILLY CO ELI (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1036064-A1 | SELECTIVE BETA 3-ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029673-A1 | SELECTIVE β3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 1999-06-17 | — | — | WO | disclosed |
| WO-1999029672-A1 | SELECTIVE β3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 1999-06-17 | — | — | WO | disclosed |