Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511015 | 0.86 | ALDH1A1 (0.38) | HPGDALDH1A1 | |
| SCHEMBL7459648 | 0.74 | GAA (0.38) | AKT1AKT2 | |
| SCHEMBL2387915 | 0.70 | KDM4E (0.41) | HPGDALDH1A1 | |
| SCHEMBL10169 | 0.68 | — | — | |
| SCHEMBL30854860 | 0.68 | — | — | |
| SCHEMBL31428680 | 0.67 | GABRG2 (0.43) | HPGDALDH1A1 | |
| SCHEMBL69872 | 0.66 | KCNN4 (0.36) | — | |
| SCHEMBL7254281 | 0.66 | GAA (0.48) | ALDH1A1 | |
| SCHEMBL21233040 | 0.66 | KDM4E (0.39) | HPGDALDH1A1 | |
| SCHEMBL70574 | 0.66 | L3MBTL1 (0.44) | AKT1AKT2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003104189-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2003-12-18 | — | — | WO | disclosed |