Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 8/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7467316 | 0.99 | CHRM4 (0.52) | CHRM4CHRM3CACNA1GDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8869803 | 0.99 | CHRM4 (0.52) | CHRM4CHRM3CACNA1GDRD2DRD4 | |
| SCHEMBL8313258 | 0.93 | CHRM4 (0.56) | CHRM4CHRM3DRD2DRD4SIGMAR1 | |
| SCHEMBL7462282 | 0.93 | DRD2 (0.49) | CACNA1GDRD2DRD4SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL7459710 | 0.92 | DRD2 (0.49) | CHRM4CHRM3CACNA1GDRD2DRD4 | |
| SCHEMBL7471015 | 0.88 | DRD2 (0.53) | CACNA1GDRD2DRD4SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL7463586 | 0.88 | DRD2 (0.53) | CACNA1GDRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL7470176 | 0.86 | CHRM4 (0.48) | CHRM4CHRM3DRD2DRD4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7459516 | 0.85 | CHRM4 (0.50) | CHRM4CHRM3DRD2DRD4SIGMAR1 | |
| SCHEMBL7465175 | 0.85 | DRD3 (0.51) | DRD2DRD4HTR7CCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0679642-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-11-10 | — | — | EP | disclosed |
| EP-0679642-A1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |