Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7459516 | 0.99 | CHRM4 (0.50) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| SCHEMBL7458791 | 0.97 | DRD2 (0.47) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7464721 | 0.96 | CHRM4 (0.46) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| SCHEMBL7462282 | 0.94 | DRD2 (0.49) | HTR1ADRD2HTR2AHRH1DRD3 | |
| SCHEMBL8315796 | 0.93 | HTR1A (0.48) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7459710 | 0.93 | DRD2 (0.49) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL8310440 | 0.92 | HTR1A (0.47) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| SCHEMBL8313258 | 0.92 | CHRM4 (0.56) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| SCHEMBL7464684 | 0.90 | DRD2 (0.49) | CHRM4CHRM3HTR1ADRD2HTR2A | |
| SCHEMBL7471015 | 0.89 | DRD2 (0.53) | HTR1ADRD2HTR2AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |