⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025215 | 0.76 | — | — | |
| SCHEMBL23409655 | 0.75 | — | — | |
| SCHEMBL17029985 | 0.74 | THRB (0.40) | — | |
| SCHEMBL3948235 | 0.73 | — | — | |
| SCHEMBL17029984 | 0.73 | MEN1 (0.34) | — | |
| SCHEMBL4770737 | 0.73 | THRB (0.39) | — | |
| SCHEMBL22081043 | 0.73 | ALOX15 (0.35) | — | |
| SCHEMBL3079040 | 0.73 | CYP1A2 (0.48) | — | |
| SCHEMBL15925196 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL31026689 | 0.71 | ANPEP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206574-A4 | GUANIDINIUM FUNCTIONALIZED OLIGOMERS AND METHODS | ISIS PHARMACEUTICALS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-1206574-A2 | GUANIDINIUM FUNCTIONALIZED OLIGOMERS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001002423-A2 | 2'-GUANIDINYL-SUBSTITUTED OLIGONUCLEOTIDES AND GENE EXPRESSION MODULATION THEREWITH | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |