Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475788 | 0.91 | MAPT (0.40) | ALDH1A1ACHEBACE1MAPTSMN1; SMN2 | |
| SCHEMBL7468284 | 0.88 | MAPT (0.43) | ALDH1A1ACHEBACE1MAPTSMN1; SMN2 | |
| SCHEMBL7464180 | 0.82 | ACHE (0.40) | ALDH1A1ACHEBACE1MAPTSMN1; SMN2 | |
| SCHEMBL7472217 | 0.81 | EGFR (0.44) | MAPTLMNA | |
| SCHEMBL8825760 | 0.77 | PDGFRB (0.42) | ALDH1A1MAPTSMN1; SMN2LMNAPKM | |
| SCHEMBL7459991 | 0.76 | LMNA (0.52) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7476281 | 0.75 | HRH4 (0.51) | ALDH1A1ACHEBACE1MAPTSMN1; SMN2 | |
| SCHEMBL7469778 | 0.73 | MAPT (0.45) | ALDH1A1ACHEBACE1MAPTSMN1; SMN2 | |
| SCHEMBL7468270 | 0.72 | MAPT (0.40) | ALDH1A1ACHEBACE1MAPTSMN1; SMN2 | |
| SCHEMBL7470183 | 0.72 | MAPT (0.42) | ALDH1A1ACHEBACE1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |