Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455410 | 1.00 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2 | |
| Brasofensine SCHEMBL29426326 | 0.87 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL3671497 | 0.86 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2 | |
| Brasofensine SCHEMBL14762214 | 0.86 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| Brasofensine SCHEMBL539079 | 0.86 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| Brasofensine SCHEMBL1649206 | 0.86 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| Brasofensine SCHEMBL20390946 | 0.86 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| Brasofensine SCHEMBL20390950 | 0.86 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL7362088 | 0.85 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2 | |
| Brasofensine SCHEMBL5031138 | 0.85 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756596-B1 | TROPANE-2-ALDOXIME DERIVATIVES AS NEUROTRANSMITTER REUPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2002-08-21 | — | — | EP | claimed |