Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017285 | 0.88 | CAPN1 (0.46) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL14559394 | 0.87 | CTSL (0.48) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL8977043 | 0.86 | MEN1 (0.54) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL13613735 | 0.85 | CAPN1 (0.44) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL5357109 | 0.84 | TDP1 (0.50) | CTSSCTSKMEN1KMT2AGAA | |
| SCHEMBL12189910 | 0.84 | MEN1 (0.51) | CTSSCTSKMEN1KMT2AGAA | |
| SCHEMBL8248462 | 0.84 | MEN1 (0.46) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL5870246 | 0.84 | MEN1 (0.46) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL5870253 | 0.84 | MEN1 (0.46) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL5870258 | 0.84 | MEN1 (0.46) | CTSLCTSBCTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973945-A4 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS INC (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-0973945-A1 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-26 | — | — | EP | disclosed |
| US-6015887-A | PREPARING SYNTHETIC MONOMERS BY DEHYDRATIVE COUPLING OF AMINE AND ALCOHOL STARTING REAGENTS | ISIS PHARMACEUTICALS, INC. (US) | 2000-01-18 | — | — | US | disclosed |
| WO-1998046794-A1 | CHIRAL PEPTIDE NUCLEIC ACIDS AND METHODS FOR PREPARING SAME | ISIS PHARMACEUTICALS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |