⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586375 | 0.76 | — | — | |
| SCHEMBL10306587 | 0.76 | — | — | |
| SCHEMBL28227352 | 0.75 | CA1 (0.33) | — | |
| SCHEMBL15800899 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL28217965 | 0.73 | CA1 (0.32) | — | |
| SCHEMBL28800247 | 0.72 | CA1 (0.48) | — | |
| SCHEMBL12916978 | 0.70 | LMNA (0.44) | — | |
| SCHEMBL12916989 | 0.70 | ALDH1A1 (0.34) | — | |
| SCHEMBL1571785 | 0.69 | — | — | |
| SCHEMBL15912147 | 0.69 | GAA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569378-B2 | p27 protein inducer | Sakai, Toshiyuki (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20110009398-A1 | p27 Protein Inducer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-0949537-B1 | Thermally developable photosensitive material | KONISHIROKU PHOTO IND (JP) | 2002-07-31 | — | — | EP | disclosed |
| US-6214533-B1 | SUPPORT COATED WITH SILVER HALIDE EMULSION LAYER INCLUDING REDUCING AGENT, INFRARED OPTICAL SENSITIZING CYANINE DYE, AND AN ORGANIC POLYSULFIDE COMPOUND, ANTIFOGGING AGENTS, STORAGE STABILITY | KONICA CORPORATION (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0949537-A2 | Thermally developable photosensitive material | KONICA CORPORATION (JP) | 1999-10-13 | — | — | EP | disclosed |