SCHEMBL7460466

SCHEMBL7460466

Clc1ccc2c(Oc3ccc(-c4ccccc4)cc3)ccnc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR2 P21802 2/20 0.56
APP P05067 2/20 0.48
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CHKA P35790 1/20 0.46
NR4A2 P43354 1/20 0.45
SOS2 Q07890 1/20 0.45
ALK Q9UM73 1/20 0.45
PKM P14618 1/20 0.45
KDR P35968 2/20 0.45
PDGFRA P16234 1/20 0.45
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PDGFRB P09619 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GLA P06280 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7465060 0.92 APP (0.50) FGFR2APPLMNASMN1; SMN2CHKA
SCHEMBL7463576 0.91 APP (0.52) FGFR2APPLMNASMN1; SMN2CHKA
SCHEMBL7462623 0.88 LMNA (0.54) FGFR2APPLMNASMN1; SMN2NR4A2
SCHEMBL7461222 0.87 APP (0.55) FGFR2APPLMNASMN1; SMN2CHKA
SCHEMBL7456971 0.83 NR4A2 (0.51) APPLMNASMN1; SMN2NR4A2SOS2
SCHEMBL7466387 0.83 NR4A2 (0.55) FGFR2APPLMNASMN1; SMN2NR4A2
SCHEMBL7466509 0.83 LMNA (0.49) FGFR2APPLMNASMN1; SMN2NR4A2
SCHEMBL7465918 0.83 LMNA (0.49) FGFR2APPLMNASMN1; SMN2NR4A2
SCHEMBL7461823 0.83 APP (0.58) FGFR2APPLMNASMN1; SMN2KDR
SCHEMBL29453809 0.83 NR4A2 (0.55) FGFR2APPLMNASMN1; SMN2NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP claimed
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP disclosed