Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465060 | 0.97 | APP (0.50) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7461222 | 0.96 | APP (0.55) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7460466 | 0.91 | FGFR2 (0.56) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7462623 | 0.90 | LMNA (0.54) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7460710 | 0.89 | RHEB (0.51) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7529202 | 0.87 | NR4A2 (0.59) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL27324401 | 0.85 | MAPT (0.47) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7465918 | 0.85 | LMNA (0.49) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7466387 | 0.85 | NR4A2 (0.55) | APPLMNASMN1; SMN2NR4A2SOS2 | |
| SCHEMBL7456971 | 0.85 | NR4A2 (0.51) | APPLMNASMN1; SMN2NR4A2SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173482-A1 | 4-AMINOQUINOLINE COMPOUNDS FOR THE TREATMENT OF ANGIOGENESIS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-09-12 | — | — | WO | disclosed |
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| CN-1034925-A | Quinoline, quinazoline and cinnoline | LILLY CO ELI (US) | 1989-08-23 | — | — | CN | disclosed |