Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003249 | 0.77 | MAPK1 (0.43) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL10451237 | 0.77 | MAPK1 (0.43) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL10645022 | 0.73 | MAPK1 (0.47) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL7470763 | 0.72 | AHR (0.39) | TSHR | |
| SCHEMBL7462347 | 0.72 | PDK2 (0.36) | CYP3A4CYP1A2 | |
| SCHEMBL11002226 | 0.67 | MAPK1 (0.37) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL592019 | 0.63 | ADRA2A (0.53) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL29648863 | 0.63 | HTR3E (0.53) | MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL29540837 | 0.63 | ADRA2A (0.53) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL140824 | 0.63 | HTR3E (0.53) | MAPK1TDP1CYP3A4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596359-B1 | Fluorinated 1,3-benzo- and 1,3-pyrido-dioxoles, process for their preparation and their use for the preparation of plant-protective agents | BAYER AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| US-5482956-A | ANTIPROTOZOA AGENTS FOR ANIMALS OR INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| US-5420309-A | Plant saftening agents, insecticides or nematocides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | disclosed |
| EP-0597304-A1 | Use of substituted benzimidazoles | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| EP-0596359-A2 | Fluorinated 1,3-benzo- and 1,3-pyrido-dioxoles, process for their preparation and their use for the preparation of plant-protective agents | BAYER AG (DE) | 1994-05-11 | — | — | EP | disclosed |