Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003249 | 0.89 | MAPK1 (0.43) | MAPK1TDP1CYP3A4TRPA1KIF11 | |
| SCHEMBL10645022 | 0.82 | MAPK1 (0.47) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL10850783 | 0.82 | P2RY6 (0.37) | TDP1CYP3A4KIF11CYP1A2 | |
| SCHEMBL11002226 | 0.78 | MAPK1 (0.37) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL7460629 | 0.77 | MAPK1 (0.36) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL2643889 | 0.72 | KIF11 (0.44) | MAPK1TDP1CYP3A4TRPA1KIF11 | |
| SCHEMBL11114110 | 0.72 | P2RY6 (0.33) | TDP1CYP3A4 | |
| SCHEMBL30298625 | 0.71 | P2RY6 (0.37) | TDP1CYP3A4KIF11 | |
| SCHEMBL140824 | 0.70 | HTR3E (0.53) | MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL29648863 | 0.70 | HTR3E (0.53) | MAPK1TDP1CYP3A4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | disclosed |
| US-4611003-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0097862-B1 | SUBSTITUTED BENZOYL(THIO) UREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PARASITICIDES | BAYER AG (DE) | 1986-08-06 | — | — | EP | disclosed |
| EP-0097862-A1 | Substituted benzoyl(thio) ureas, process for their preparation and their use as parasiticides | BAYER AG (DE) | 1984-01-11 | — | — | EP | disclosed |