Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563746 | 0.91 | MAPT (0.49) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL7468006 | 0.90 | MAPT (0.46) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7472833 | 0.89 | MAPT (0.48) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7468043 | 0.85 | MAPT (0.48) | NLRP3MAPTLMNAMEN1KMT2A | |
| SCHEMBL7461911 | 0.85 | MAPT (0.44) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL7468103 | 0.85 | GAA (0.44) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7465177 | 0.84 | S1PR2 (0.49) | MAPTLMNAMEN1KMT2AKDM4E | |
| Iodide SCHEMBL7462209 | 0.84 | MAPT (0.41) | MAPTLMNAMEN1KMT2AKDM4E | |
| Iodide SCHEMBL7468583 | 0.83 | MAPT (0.43) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| Iodide SCHEMBL4455368 | 0.83 | MAPT (0.40) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |