Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PARG | Q86W56 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472833 | 0.95 | MAPT (0.48) | MAPTTP53THRBALDH1A1LMNA | |
| SCHEMBL7468006 | 0.91 | MAPT (0.46) | MAPTTP53ALDH1A1LMNAMEN1 | |
| SCHEMBL7460699 | 0.91 | NLRP3 (0.45) | MAPTTP53THRBKDM4EALDH1A1 | |
| SCHEMBL7468103 | 0.90 | GAA (0.44) | MAPTTP53THRBALDH1A1LMNA | |
| SCHEMBL7468043 | 0.89 | MAPT (0.48) | MAPTTP53THRBKDM4ELMNA | |
| SCHEMBL7461911 | 0.89 | MAPT (0.44) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL7457276 | 0.88 | MAPT (0.47) | MAPTTP53THRBKDM4EALDH1A1 | |
| Iodide SCHEMBL7468583 | 0.88 | MAPT (0.43) | MAPTTP53THRBPARGALDH1A1 | |
| SCHEMBL7465177 | 0.87 | S1PR2 (0.49) | MAPTTP53KDM4EALDH1A1LMNA | |
| Iodide SCHEMBL7462209 | 0.87 | MAPT (0.41) | MAPTTP53THRBPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224945-A1 | TENSION-RELIEVING AGENTS FOR CILIARY MUSCLE | Senju Pharmaceutical Co., Ltd. (JP) | 2002-07-24 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |