Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563746 | 0.87 | MAPT (0.49) | S1PR2TP53MAPTHDAC6RXFP1 | |
| SCHEMBL7472833 | 0.86 | MAPT (0.48) | TP53MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7468006 | 0.85 | MAPT (0.46) | S1PR2TP53MAPTALDH1A1MEN1 | |
| SCHEMBL7463810 | 0.84 | SMN1; SMN2 (0.45) | S1PR2TP53HDAC6ALDH1A1MEN1 | |
| SCHEMBL7460699 | 0.84 | NLRP3 (0.45) | TP53MAPTRXFP1ALDH1A1MEN1 | |
| SCHEMBL7470111 | 0.83 | ALDH1A1 (0.50) | S1PR2TP53MAPTRXFP1ALDH1A1 | |
| SCHEMBL7465395 | 0.82 | TP53 (0.51) | TP53MAPTHDAC6ALDH1A1CMA1 | |
| SCHEMBL7468103 | 0.82 | GAA (0.44) | TP53MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7566236 | 0.82 | LMNA (0.41) | S1PR2TP53MAPTHDAC6ALDH1A1 | |
| SCHEMBL7468043 | 0.81 | MAPT (0.48) | TP53MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |