Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468006 | 0.96 | MAPT (0.46) | MAPTTP53GAAMEN1KMT2A | |
| SCHEMBL7563746 | 0.95 | MAPT (0.49) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL7461911 | 0.93 | MAPT (0.44) | MAPTTP53GAAMEN1KMT2A | |
| SCHEMBL7468103 | 0.93 | GAA (0.44) | MAPTTP53GAAMEN1KMT2A | |
| Iodide SCHEMBL7468583 | 0.91 | MAPT (0.43) | MAPTTP53GAAMEN1KMT2A | |
| SCHEMBL7460699 | 0.89 | NLRP3 (0.45) | MAPTTP53GAAMEN1KMT2A | |
| SCHEMBL7465888 | 0.88 | ALDH1A1 (0.50) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL7468043 | 0.88 | MAPT (0.48) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL7460299 | 0.87 | MAPT (0.43) | MAPTTP53MEN1KMT2ACMA1 | |
| SCHEMBL7467191 | 0.87 | L3MBTL1 (0.45) | MAPTTP53GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |