Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468835 | 1.00 | TLR4 (0.32) | TLR4TLR2HRH3MAPT | |
| SCHEMBL7468045 | 0.91 | MAPT (0.34) | MAPT | |
| SCHEMBL7460652 | 0.91 | MAPT (0.34) | MAPT | |
| SCHEMBL7473197 | 0.84 | HRH3 (0.33) | TLR4TLR2HRH3MAPT | |
| SCHEMBL7469316 | 0.83 | ADRB3 (0.42) | HRH3MAPT | |
| SCHEMBL7465477 | 0.81 | MAPT (0.35) | TLR4TLR2MAPT | |
| SCHEMBL7470305 | 0.78 | MAPT (0.37) | MAPT | |
| SCHEMBL7470143 | 0.74 | MAPT (0.36) | MAPT | |
| SCHEMBL7827854 | 0.73 | RXRA (0.36) | MAPT | |
| SCHEMBL7823802 | 0.71 | BRD4 (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214313-A2 | HETEROARYLOXY PROPANOLAMINES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001017989-A2 | HETEROARYLOXYPROPANOLAMINES AS BETA3-ADRENERGIC RECEPTOR AGONISTS | SANOFI-SYNTHELABO (FR) | 2001-03-15 | — | — | WO | disclosed |