Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827854 | 0.90 | RXRA (0.36) | BRD4ABCB1RXRAMAPTUSP2 | |
| SCHEMBL12380684 | 0.78 | MAPT (0.37) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL2295690 | 0.78 | MAPT (0.37) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL2295688 | 0.78 | MAPT (0.37) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL7472518 | 0.77 | LMNA (0.45) | MAPTMAPK1NPSR1MEN1KMT2A | |
| SCHEMBL7470305 | 0.77 | MAPT (0.37) | ABCB1MAPTUSP2TSHRMAPK1 | |
| SCHEMBL5263655 | 0.76 | LMNA (0.43) | ABCB1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL3286843 | 0.76 | LMNA (0.43) | ABCB1MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL5203047 | 0.74 | ADRB3 (0.48) | MAPTMAPK1NPSR1MEN1KMT2A | |
| SCHEMBL7812791 | 0.74 | CACNA1B (0.45) | MAPTTSHRMAPK1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087961-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065895-A1 | PHENOXYLPROPANOLAMINES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SANOFI-SYNTHELABO (FR) | 1999-12-23 | — | — | WO | disclosed |