Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472430 | 0.83 | SMN1; SMN2 (0.39) | EGFRPDGFRBALDH1A1MAPTLMNA | |
| SCHEMBL7473900 | 0.81 | EGFR (0.56) | EGFRPDGFRBMAPTLMNAABCG2 | |
| SCHEMBL7460996 | 0.81 | EGFR (0.48) | EGFRPDGFRBALDH1A1MAPTLMNA | |
| SCHEMBL7529433 | 0.78 | EGFR (0.51) | EGFRPDGFRBALDH1A1MAPTLMNA | |
| SCHEMBL7470644 | 0.76 | EGFR (0.53) | EGFRPDGFRBABCG2 | |
| SCHEMBL7466558 | 0.75 | EGFR (0.46) | EGFRPDGFRBABCG2CNR1 | |
| SCHEMBL7474113 | 0.74 | EGFR (0.55) | EGFRPDGFRBALDH1A1MAPTLMNA | |
| SCHEMBL7475452 | 0.73 | EGFR (0.52) | EGFRPDGFRBABCG2 | |
| SCHEMBL7460865 | 0.73 | CHRM4 (0.47) | EGFRALDH1A1CNR1CNR2KMT2A | |
| SCHEMBL7472380 | 0.72 | EGFR (0.53) | EGFRPDGFRBMAPTHTTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |