Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472421 | 0.83 | POLB (0.47) | CHRM4EGFRCTNNB1TCF7L2TTK | |
| SCHEMBL7473897 | 0.82 | EGFR (0.55) | EGFRMAPK1 | |
| SCHEMBL7473179 | 0.82 | MAPK1 (0.58) | EGFRCNR1CNR2MAPK1 | |
| SCHEMBL7472725 | 0.81 | EGFR (0.61) | EGFRMAPK1 | |
| SCHEMBL7460987 | 0.81 | PDE5A (0.53) | EGFRCNR1PDE5AALDH1A1MAPK1 | |
| SCHEMBL7461665 | 0.80 | USP10 (0.59) | EGFRCNR1CNR2KMT2AMAPK1 | |
| SCHEMBL7465009 | 0.80 | HTT (0.57) | EGFRKMT2AALDH1A1MAPK1 | |
| SCHEMBL7475194 | 0.80 | EGFR (0.66) | EGFRMAPK1 | |
| SCHEMBL7469854 | 0.80 | EGFR (0.56) | EGFRCNR1CNR2MAPK1 | |
| SCHEMBL7529420 | 0.79 | LMNA (0.52) | EGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |