Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461854 | 0.90 | ALDH1A1 (0.41) | GAAALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL7679306 | 0.85 | ALDH1A1 (0.40) | GAAALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL7460856 | 0.84 | PDE4A (0.36) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL7456776 | 0.83 | PDE4A (0.37) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL7459262 | 0.81 | EPHX1 (0.54) | GAAALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL7458253 | 0.81 | PDE4A (0.38) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL7686045 | 0.80 | HPGD (0.44) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL7466102 | 0.80 | ALDH1A1 (0.50) | GAAALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7458185 | 0.77 | MAPT (0.39) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL7456728 | 0.76 | HTT (0.47) | ALDH1A1NPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002540193-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165515-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | claimed |
| WO-2000058288-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | claimed |