Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459262 | 0.84 | EPHX1 (0.54) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7683202 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAATSHRNPSR1LMNA | |
| SCHEMBL7461854 | 0.81 | ALDH1A1 (0.41) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7460958 | 0.80 | GAA (0.40) | ALDH1A1GAAKMT2ATP53SMN1; SMN2 | |
| SCHEMBL7458253 | 0.73 | PDE4A (0.38) | ALDH1A1TSHRKMT2AL3MBTL1TDP1 | |
| SCHEMBL7523711 | 0.73 | RAB9A (0.51) | ALDH1A1LMNAKMT2ARAB9AMAPT | |
| SCHEMBL7456728 | 0.73 | HTT (0.47) | ALDH1A1KMT2ARAB9AMAPT | |
| SCHEMBL7675174 | 0.72 | ALDH1A1 (0.46) | ALDH1A1TSHRNPSR1KMT2ATP53 | |
| SCHEMBL6949794 | 0.71 | HDAC1 (0.36) | KMT2AL3MBTL1TDP1HSD17B10CCNE1 | |
| SCHEMBL7456776 | 0.70 | PDE4A (0.37) | ALDH1A1TSHRLMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165515-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058288-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |