Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460856 | 0.88 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL7458253 | 0.87 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL7680208 | 0.85 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL6949924 | 0.84 | CCNE1 (0.35) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL7460958 | 0.83 | GAA (0.40) | CCNE1CDK2ALDH1A1ITGB1ITGA4 | |
| SCHEMBL7461854 | 0.83 | ALDH1A1 (0.41) | CCNE1CDK2ALDH1A1LMNAPOLB | |
| SCHEMBL6949794 | 0.79 | HDAC1 (0.36) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL7464085 | 0.78 | PDE4D (0.42) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7683047 | 0.78 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DCCNE1 | |
| SCHEMBL7684169 | 0.77 | ALDH1A1 (0.37) | PDE4APDE4BPDE4CPDE4DCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002540193-A | — | — | 2002-11-26 | — | — | JP | claimed |
| EP-1165515-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | claimed |
| WO-2000058288-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | claimed |