Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | PTGFR | P43088 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472840 | 0.90 | MEN1 (0.41) | KMT2ARAB9AMEN1CHEK1ITGB1 | |
| SCHEMBL7463043 | 0.90 | RAB9A (0.50) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7467296 | 0.90 | RAB9A (0.50) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7467339 | 0.88 | KMT2A (0.45) | KMT2ARAB9AMEN1ALDH1A1MAPK1 | |
| SCHEMBL7461109 | 0.88 | KMT2A (0.45) | KMT2ARAB9AMEN1ALDH1A1MAPK1 | |
| SCHEMBL7468535 | 0.81 | ATM (0.45) | KMT2AMEN1CHEK1ITGB1ITGA4 | |
| SCHEMBL7473206 | 0.81 | ATM (0.45) | KMT2AMEN1CHEK1ITGB1ITGA4 | |
| SCHEMBL7471656 | 0.80 | KMT2A (0.43) | KMT2ARAB9AMAPTMEN1CHEK1 | |
| SCHEMBL7471806 | 0.80 | KMT2A (0.43) | KMT2ARAB9AMAPTMEN1CHEK1 | |
| SCHEMBL7464092 | 0.80 | RAB9A (0.48) | KMT2ANPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |