Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471806 | 1.00 | KMT2A (0.43) | KMT2AMEN1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL7470798 | 0.92 | RAB9A (0.42) | KMT2AMEN1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL7466040 | 0.90 | ITGB1 (0.46) | KMT2AMEN1NPSR1ITGB1ITGA4 | |
| SCHEMBL7466308 | 0.90 | ITGB1 (0.46) | KMT2AMEN1NPSR1ITGB1ITGA4 | |
| SCHEMBL7472840 | 0.90 | MEN1 (0.41) | KMT2AMEN1RAB9AITGB1ITGA4 | |
| SCHEMBL7467208 | 0.82 | ITGB1 (0.42) | KMT2AMEN1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL7465560 | 0.82 | ITGB1 (0.42) | KMT2AMEN1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL7461541 | 0.80 | KMT2A (0.42) | KMT2AMEN1RAB9AITGB1ITGA4 | |
| SCHEMBL7467339 | 0.80 | KMT2A (0.45) | KMT2AMEN1RAB9AITGB1ITGA4 | |
| SCHEMBL7461109 | 0.80 | KMT2A (0.45) | KMT2AMEN1RAB9AITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |