Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461541 | 0.90 | KMT2A (0.42) | MEN1KMT2AITGB1ITGA4CHEK1 | |
| SCHEMBL7473206 | 0.90 | ATM (0.45) | MEN1KMT2AITGB1ITGA4CHEK1 | |
| SCHEMBL7468535 | 0.90 | ATM (0.45) | MEN1KMT2AITGB1ITGA4CHEK1 | |
| SCHEMBL7471806 | 0.90 | KMT2A (0.43) | MEN1KMT2AITGB1ITGA4CHEK1 | |
| SCHEMBL7471656 | 0.90 | KMT2A (0.43) | MEN1KMT2AITGB1ITGA4CHEK1 | |
| SCHEMBL7466040 | 0.86 | ITGB1 (0.46) | MEN1KMT2AITGB1ITGA4CTSD | |
| SCHEMBL7466308 | 0.86 | ITGB1 (0.46) | MEN1KMT2AITGB1ITGA4CTSD | |
| SCHEMBL7467449 | 0.82 | ATM (0.43) | MEN1KMT2AITGB1ITGA4EPHX2 | |
| SCHEMBL7466878 | 0.82 | ATM (0.43) | MEN1KMT2AITGB1ITGA4EPHX2 | |
| SCHEMBL7470798 | 0.82 | RAB9A (0.42) | MEN1KMT2AITGB1ITGA4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |