Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 1/20 | 0.59 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.59 |
| ▸ | USP13 | Q92995 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 8/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473179 | 0.91 | MAPK1 (0.58) | EGFRHTTCNR1CNR2MAPK1 | |
| SCHEMBL7472725 | 0.90 | EGFR (0.61) | USP10PIK3C3USP13EGFRHTT | |
| SCHEMBL7460787 | 0.89 | EGFR (0.51) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7464363 | 0.89 | HTT (0.54) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7473897 | 0.89 | EGFR (0.55) | USP10PIK3C3USP13EGFRHTT | |
| SCHEMBL7465009 | 0.89 | HTT (0.57) | EGFRHTTMAPK1LMNAMEN1 | |
| SCHEMBL7475194 | 0.89 | EGFR (0.66) | EGFRHTTMAPK1LMNA | |
| SCHEMBL7469106 | 0.88 | CLK4 (0.58) | EGFRHTTCNR1CNR2MAPK1 | |
| SCHEMBL7469854 | 0.88 | EGFR (0.56) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL7463417 | 0.87 | EGFR (0.49) | USP10PIK3C3USP13EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |