Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473179 | 0.91 | MAPK1 (0.58) | HTTEGFRMAPK1MAPTL3MBTL1 | |
| SCHEMBL7472725 | 0.90 | EGFR (0.61) | HTTEGFRMAPK1 | |
| SCHEMBL7475626 | 0.89 | HTT (0.52) | HTTALDH1A1KDM4EEGFRMAPK1 | |
| SCHEMBL7473897 | 0.89 | EGFR (0.55) | HTTEGFRMAPK1 | |
| SCHEMBL7461665 | 0.89 | USP10 (0.59) | HTTEGFRMAPK1LMNAMEN1 | |
| SCHEMBL7475194 | 0.89 | EGFR (0.66) | HTTKDM4EEGFRMAPK1LMNA | |
| SCHEMBL7474668 | 0.88 | HTT (0.63) | HTTALDH1A1KDM4ENPC1EGFR | |
| SCHEMBL7470641 | 0.86 | EGFR (0.50) | ALDH1A1EGFRMAPK1LMNA | |
| SCHEMBL7469854 | 0.86 | EGFR (0.56) | EGFRMAPK1LMNA | |
| SCHEMBL7529420 | 0.86 | LMNA (0.52) | NPC1EGFRMAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |