Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.56 |
| ▸ | CNR1 | P21554 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 3/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | USP10 | Q14694 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | USP13 | Q92995 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461665 | 0.88 | USP10 (0.59) | EGFRCNR1LMNAMAPK1USP10 | |
| SCHEMBL7473179 | 0.88 | MAPK1 (0.58) | EGFRCNR1LMNAMAPK1CNR2 | |
| SCHEMBL7472725 | 0.87 | EGFR (0.61) | EGFRAURKARPS6KB1MAPK1USP10 | |
| SCHEMBL7473897 | 0.86 | EGFR (0.55) | EGFRMAPK1USP10PIK3C3USP13 | |
| SCHEMBL7465009 | 0.86 | HTT (0.57) | EGFRLMNAMAPK1 | |
| SCHEMBL7475194 | 0.86 | EGFR (0.66) | EGFRLMNAMAPK1 | |
| SCHEMBL7460787 | 0.84 | EGFR (0.51) | EGFRCNR1AURKARPS6KB1MAPK1 | |
| SCHEMBL7474668 | 0.83 | HTT (0.63) | EGFRLMNAMAPK1 | |
| SCHEMBL7470641 | 0.83 | EGFR (0.50) | EGFRLMNAMAPK1 | |
| SCHEMBL7469106 | 0.81 | CLK4 (0.58) | EGFRCNR1LMNAAURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |