Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | USP10 | Q14694 | 1/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
| ▸ | USP13 | Q92995 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473179 | 0.91 | MAPK1 (0.58) | EGFRHTTMAPK1 | |
| SCHEMBL7472725 | 0.90 | EGFR (0.61) | EGFRHTTMAPK1USP10PIK3C3 | |
| SCHEMBL7474665 | 0.89 | HTT (0.62) | EGFRHTTMAPK1NR2F2ALK | |
| SCHEMBL7465009 | 0.89 | HTT (0.57) | EGFRHTTMAPK1 | |
| SCHEMBL7461665 | 0.89 | USP10 (0.59) | EGFRHTTMAPK1USP10PIK3C3 | |
| SCHEMBL7475194 | 0.89 | EGFR (0.66) | EGFRHTTMAPK1NR2F2 | |
| SCHEMBL7474668 | 0.86 | HTT (0.63) | EGFRHTTMAPK1NR2F2 | |
| SCHEMBL7469854 | 0.86 | EGFR (0.56) | EGFRMAPK1USP10PIK3C3USP13 | |
| SCHEMBL7470641 | 0.86 | EGFR (0.50) | EGFRMAPK1 | |
| SCHEMBL7529420 | 0.86 | LMNA (0.52) | EGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |