Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15423257 | 0.82 | POLB (0.55) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL15423258 | 0.82 | DRD2 (0.56) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL10248078 | 0.81 | POLB (0.56) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL764345 | 0.80 | POLB (0.55) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL16264966 | 0.79 | DRD2 (0.58) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL1764705 | 0.79 | ALDH1A1 (0.55) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL13618147 | 0.78 | DRD2 (0.61) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL1763884 | 0.78 | DRD2 (0.57) | SMPD1CHRM1DRD2HTR2AMCHR1 | |
| SCHEMBL4058329 | 0.77 | ALDH1A1 (0.56) | SMPD1CHRM1POLBHSD17B10DRD2 | |
| SCHEMBL318658 | 0.76 | TSHR (0.58) | SMPD1CHRM1POLBHSD17B10DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068191-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999050257-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | disclosed |