Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5869030 | 0.86 | GSK3B (0.40) | EGLN2 | |
| SCHEMBL7465214 | 0.85 | VCP (0.45) | VCP | |
| SCHEMBL5869023 | 0.83 | HDAC1 (0.42) | — | |
| SCHEMBL5868787 | 0.83 | HDAC1 (0.42) | — | |
| SCHEMBL7558106 | 0.82 | HCRTR1 (0.37) | VCP | |
| SCHEMBL7467127 | 0.82 | VCP (0.42) | VCP | |
| SCHEMBL5868972 | 0.81 | MAPK14 (0.44) | EGLN2 | |
| SCHEMBL5869064 | 0.81 | GSK3B (0.39) | EGLN2 | |
| SCHEMBL5869010 | 0.80 | KCNQ4 (0.45) | EGLN2 | |
| SCHEMBL5868798 | 0.80 | LMNA (0.41) | EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224175-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001029012-A2 | BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-26 | — | — | WO | disclosed |