Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306207 | 0.89 | HSP90AA1 (0.59) | DYRK1ACHRNA7KMT2AMEN1KDM4E | |
| SCHEMBL7462194 | 0.86 | ADORA1 (0.49) | MAOBDYRK1ACHRNA7ACHEKMT2A | |
| SCHEMBL17144809 | 0.81 | CYP1A1 (0.54) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL1388381 | 0.78 | DYRK1A (0.66) | MAOBDYRK1ADHFRKMT2AMEN1 | |
| SCHEMBL6749872 | 0.76 | HSP90AA1 (0.61) | MAOBKMT2AMEN1KDM4EMAPT | |
| SCHEMBL7598921 | 0.75 | CYP1A1 (0.61) | KMT2AMEN1KDM4EMAPTNPC1 | |
| SCHEMBL30507464 | 0.74 | GSK3B (0.60) | DYRK1ACHRNA7KMT2AMEN1KDM4E | |
| SCHEMBL28512792 | 0.74 | GSK3B (0.60) | DYRK1ACHRNA7KMT2AMEN1KDM4E | |
| SCHEMBL509183 | 0.74 | KDM4E (0.52) | MAOBDHFRACHEKMT2AMEN1 | |
| SCHEMBL12306204 | 0.73 | KDM4E (0.63) | MAOBKMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767170-B1 | NOVEL 4,6-DIARYLPYRIMIDINE DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-5786355-A | COMPOUNDS FOR TREATMENT OF CANCER, RHEUMATISM, DIABETIC RETINOPATHY OR PSORIASIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0767170-A1 | NOVEL 4,6-DIARYLPYRIMIDINE DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-09 | — | — | EP | disclosed |