Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 6/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468264 | 0.90 | PAK1 (0.48) | PAK1PDGFRBKITPDGFRAFLT3 | |
| SCHEMBL7464723 | 0.90 | PDGFRB (0.51) | PAK1PDGFRBKITPDGFRAFLT3 | |
| SCHEMBL7458947 | 0.84 | CCR6 (0.46) | — | |
| SCHEMBL7467371 | 0.84 | NSD2 (0.53) | — | |
| SCHEMBL7467225 | 0.82 | PAK1 (0.46) | PAK1PDGFRBALDH1A1 | |
| SCHEMBL7462111 | 0.82 | CYP1A2 (0.40) | PAK1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7463135 | 0.81 | CNR1 (0.53) | PAK1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7463150 | 0.78 | CYP1A2 (0.41) | PAK1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7469270 | 0.78 | KMT2A (0.49) | PAK1ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL7459198 | 0.77 | MEN1 (0.53) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |