Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458931 | 0.90 | NSD2 (0.56) | NSD2MEN1KMT2ACNR1MAPT | |
| SCHEMBL7458947 | 0.86 | CCR6 (0.46) | CNR1KDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL7462115 | 0.84 | PAK1 (0.58) | — | |
| SCHEMBL7459198 | 0.84 | MEN1 (0.53) | MEN1KMT2AHTTKDM4ELMNA | |
| SCHEMBL7462111 | 0.84 | CYP1A2 (0.40) | NSD2CNR1MAPTHTTKDM4E | |
| SCHEMBL7471138 | 0.82 | MAPT (0.45) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL7463395 | 0.77 | HTT (0.55) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL7463150 | 0.77 | CYP1A2 (0.41) | MEN1KMT2ACNR1MAPTHTT | |
| SCHEMBL7463135 | 0.76 | CNR1 (0.53) | CNR1MAPTKDM4ELMNAMAPK1 | |
| SCHEMBL7470513 | 0.76 | CNR1 (0.53) | KMT2ACNR1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |