Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 6/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469270 | 0.91 | KMT2A (0.49) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL7464723 | 0.89 | PDGFRB (0.51) | MAPTPAK1 | |
| SCHEMBL7466525 | 0.87 | MAPT (0.47) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL7467225 | 0.86 | PAK1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2PAK1 | |
| SCHEMBL7463150 | 0.86 | CYP1A2 (0.41) | CNR1CNR2ALDH1A1MAPTPAK1 | |
| SCHEMBL7475884 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNASMN1; SMN2GPR174 | |
| SCHEMBL7458931 | 0.84 | NSD2 (0.56) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL7470513 | 0.84 | CNR1 (0.53) | CNR1CNR2ALDH1A1MAPTLMNA | |
| SCHEMBL7468264 | 0.83 | PAK1 (0.48) | PAK1 | |
| SCHEMBL7464718 | 0.82 | CYP1A2 (0.37) | CNR1CNR2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |