Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.51 |
| ▸ | PAK1 | Q13153 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468264 | 0.92 | PAK1 (0.48) | PDGFRBPAK1POLBKITPDGFRA | |
| SCHEMBL7467225 | 0.91 | PAK1 (0.46) | PDGFRBPAK1MAPTPOLB | |
| SCHEMBL7462115 | 0.90 | PAK1 (0.58) | PDGFRBPAK1KITPDGFRAFLT3 | |
| SCHEMBL7463135 | 0.89 | CNR1 (0.53) | PAK1MAPT | |
| SCHEMBL7463150 | 0.85 | CYP1A2 (0.41) | PAK1MAPT | |
| SCHEMBL7458931 | 0.83 | NSD2 (0.56) | MAPTNPSR1 | |
| SCHEMBL7470513 | 0.82 | CNR1 (0.53) | MAPT | |
| SCHEMBL7469270 | 0.82 | KMT2A (0.49) | PAK1MAPTNPSR1 | |
| SCHEMBL7464718 | 0.80 | CYP1A2 (0.37) | MAPT | |
| SCHEMBL7469276 | 0.80 | MAPT (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |