Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462298 | 1.00 | SCN1A (0.38) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL7462371 | 0.91 | SCN1A (0.41) | SCN1ASCN2ASCN3APOLB | |
| SCHEMBL7462375 | 0.91 | SCN1A (0.41) | SCN1ASCN2ASCN3APOLB | |
| SCHEMBL7465346 | 0.88 | LMNA (0.34) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL7465335 | 0.88 | LMNA (0.34) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL7464282 | 0.88 | LMNA (0.34) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL7464291 | 0.88 | LMNA (0.34) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL7466710 | 0.87 | POLB (0.36) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL2761998 | 0.80 | PARP1 (0.34) | MEN1KMT2A | |
| SCHEMBL2762080 | 0.80 | PARP1 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098894-B1 | FKBP INHIBITORS | PFIZER LTD (GB) | 2002-10-02 | — | — | EP | disclosed |