Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.56 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 10/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462410 | 1.00 | PIM1 (0.56) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7453501 | 0.88 | PIM1 (0.56) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7460614 | 0.88 | HPGD (0.55) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7525440 | 0.88 | HPGD (0.55) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7463022 | 0.86 | MAOA (0.56) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7459750 | 0.86 | MAOA (0.56) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7457308 | 0.82 | NPC1 (0.64) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7467062 | 0.82 | NPC1 (0.64) | PIM1PIM2HPGDMAOAMAOB | |
| SCHEMBL7461128 | 0.82 | PKM (0.54) | HPGDPOLB | |
| SCHEMBL6359955 | 0.80 | MAOA (0.56) | PIM1PIM2HPGDMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971917-B1 | THIAZOLIDINEDIONE AND OXAZOLIDINEDIONE DERIVATIVES HAVING ANTIDIABETIC, HYPOLIPIDAEMIC AND ANTIHYPERTENSIVE PROPERTIES | REDDY RESEARCH FOUNDATION (IN) | 2002-02-06 | — | — | EP | claimed |