SCHEMBL7463045

SCHEMBL7463045

Cc1cc(OC(=O)Cl)c(C)o1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
KDM4E B2RXH2 4/20 0.40
ALOX5 P09917 2/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 7/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
RECQL P46063 1/20 0.35
NQO1 P15559 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6142432 0.81 MAPT (0.41) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL8038327 0.79 MAPT (0.44) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL10499093 0.78 MAPT (0.43) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL9566155 0.75 MAPT (0.37) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL9566156 0.75 MAPT (0.41) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL10765891 0.73 MAPT (0.43) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL9566159 0.72 MAPT (0.33) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL11131991 0.70
SCHEMBL388833 0.70 MAPT (0.62) MAPTKDM4ERAB9AALDH1A1SMN1; SMN2
SCHEMBL9817942 0.69 NPC1 (0.37) MAPTKDM4EALOX5RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0005509-B1 PROCESS FOR THE PREPARATION OF O-METHYL-N-CYCLOHEXYL-2,5-DIMETHYL-3-FURANHYDROXAMIC ACID BASF Aktiengesellschaft (DE) 1981-04-15 EP claimed
EP-0005509-A2 Process for the preparation of O-methyl-N-cyclohexyl-2,5-dimethyl-3-furanhydroxamic acid BASF Aktiengesellschaft (DE) 1979-11-28 EP claimed
EP-0994865-B1 TRIAZOLE COMPOUNDS AND THE USE THEREOF AS DOPAMINE-D 3-LIGANDS BASF AG (DE) 2002-03-06 EP disclosed
EP-0994865-A1 TRIAZOLE COMPOUNDS AND THE USE THEREOF AS DOPAMINE-D 3?-LIGANDS BASF AKTIENGESELLSCHAFT (DE) 2000-04-26 EP disclosed
WO-1999002503-A1 TRIAZOLE COMPOUNDS AND THE USE THEREOF AS DOPAMINE-D3-LIGANDS BASF AKTIENGESELLSCHAFT (DE) 1999-01-21 WO disclosed
EP-0349862-B1 2,6 polyalkyl piperidine-4-amides, their use as stabilizers in particular for synthetic materials as well as the organic material containing them BASF AG (DE) 1993-10-27 EP disclosed
EP-0258790-B1 FURAN- OR THIOPHENECARBOXYLIC-ACID PROPARGYL ESTERS BASF Aktiengesellschaft (DE) 1991-10-09 EP disclosed
EP-0349862-A1 2,6 polyalkyl piperidine-4-amides, their use as stabilizers in particular for synthetic materials as well as the organic material containing them BASF Aktiengesellschaft (DE) 1990-01-10 EP disclosed
EP-0149781-B1 FURANE-3-CARBOXYLIC-ACID DERIVATIVES BASF Aktiengesellschaft (DE) 1989-02-22 EP disclosed
EP-0258790-A2 Furan- or thiophenecarboxylic-acid propargyl esters BASF Aktiengesellschaft (DE) 1988-03-09 EP disclosed
EP-0149781-A1 Furane-3-carboxylic-acid derivatives BASF Aktiengesellschaft (DE) 1985-07-31 EP disclosed
EP-0008370-B1 N-CYCLOHEXYL-N-METHOXY-ACETOACETAMIDE, PROCESS FOR ITS PREPARATION AND ITS USE TO PREPARE O-METHYL-N-CYCLOHEXYL-2,5-DIMETHYL-FURANE-3-HYDROXAMIC ACID BASF Aktiengesellschaft (DE) 1981-12-02 EP disclosed
EP-0005509-B1 PROCESS FOR THE PREPARATION OF O-METHYL-N-CYCLOHEXYL-2,5-DIMETHYL-3-FURANHYDROXAMIC ACID BASF Aktiengesellschaft (DE) 1981-04-15 EP disclosed
EP-0017931-A2 4H-3,1-Benzoxazine derivatives, methods of their preparation and their use in combating undesirable vegetation BASF Aktiengesellschaft (DE) 1980-10-29 EP disclosed
EP-0008370-A2 N-Cyclohexyl-N-methoxy-acetoacetamide, process for its preparation and its use to prepare O-methyl-N-cyclohexyl-2,5-dimethyl-furane-3-hydroxamic acid BASF Aktiengesellschaft (DE) 1980-03-05 EP disclosed
EP-0005509-A2 Process for the preparation of O-methyl-N-cyclohexyl-2,5-dimethyl-3-furanhydroxamic acid BASF Aktiengesellschaft (DE) 1979-11-28 EP disclosed
EP-0005509-A2 Process for the preparation of O-methyl-N-cyclohexyl-2,5-dimethyl-3-furanhydroxamic acid BASF Aktiengesellschaft (DE) 1979-11-28 EP disclosed