SCHEMBL8038327

SCHEMBL8038327

Cc1cc(OC(N)=O)c(C)o1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
KDM4E B2RXH2 1/20 0.44
ALOX5 P09917 2/20 0.43
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
POLB P06746 1/20 0.37
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
RECQL P46063 1/20 0.35
NQO1 P15559 1/20 0.34
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6142432 0.81 MAPT (0.41) MAPTKDM4EALOX5MEN1KMT2A
SCHEMBL7463045 0.79 MAPT (0.40) MAPTKDM4EALOX5MEN1KMT2A
SCHEMBL9566156 0.79 MAPT (0.41) MAPTKDM4EALOX5MEN1KMT2A
SCHEMBL10499093 0.78 MAPT (0.43) MAPTKDM4EALOX5RAB9AALDH1A1
SCHEMBL10765891 0.77 MAPT (0.43) MAPTKDM4EALOX5MEN1KMT2A
SCHEMBL9566155 0.75 MAPT (0.37) MAPTKDM4EALOX5MEN1KMT2A
SCHEMBL9566159 0.72 MAPT (0.33) MAPTKDM4EALOX5MEN1KMT2A
SCHEMBL11131991 0.70
SCHEMBL5799680 0.70 MAPT (0.62) MAPTKDM4EALOX5POLBRAB9A
SCHEMBL7752902 0.69 ALOX5 (0.42) KDM4EALOX5MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0988293-A1 BISIMINO-SUBSTITUTED PHENYL COMPOUNDS AND THEIR USE AS PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-03-29 EP disclosed
WO-1998056774-A1 BISIMINO-SUBSTITUTED PHENYL COMPOUNDS AND THEIR USE AS PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-12-17 WO disclosed
EP-0006149-B1 PROCESS FOR THE PREPARATION OF ALKYL ESTERS OF 2,5-DIMETHYLFURAN-3-CARBOXYLIC ACID BASF Aktiengesellschaft (DE) 1982-01-06 EP disclosed