Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142432 | 0.74 | MAPT (0.41) | MAPTKDM4EALDH1A1NQO1MEN1 | |
| SCHEMBL7463045 | 0.72 | MAPT (0.40) | MAPTKDM4EALDH1A1NQO1MEN1 | |
| SCHEMBL8038327 | 0.72 | MAPT (0.44) | MAPTKDM4EALDH1A1NQO1MEN1 | |
| SCHEMBL9566155 | 0.72 | MAPT (0.37) | MAPTKDM4EALDH1A1NQO1MEN1 | |
| SCHEMBL10499093 | 0.71 | MAPT (0.43) | MAPTKDM4EALDH1A1GLASMN1; SMN2 | |
| SCHEMBL9566156 | 0.68 | MAPT (0.41) | MAPTKDM4EALDH1A1MEN1GLA | |
| SCHEMBL10765891 | 0.67 | MAPT (0.43) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL23204805 | 0.67 | KDM4E (0.41) | MAPTKDM4EALDH1A1MEN1CYP3A4 | |
| SCHEMBL31044542 | 0.64 | MAPT (0.48) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3183646 | 0.63 | CA12 (0.38) | CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571031-A2 | Process for the preparation of savoury flavours | QUEST INTERNATIONAL B.V. (NL) | 1993-11-24 | — | — | EP | disclosed |