Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142432 | 0.76 | MAPT (0.41) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL7463045 | 0.75 | MAPT (0.40) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL8038327 | 0.75 | MAPT (0.44) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL10499093 | 0.73 | MAPT (0.43) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL9566159 | 0.72 | MAPT (0.33) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL9566156 | 0.70 | MAPT (0.41) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL10765891 | 0.69 | MAPT (0.43) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL11131991 | 0.66 | — | — | |
| SCHEMBL9817942 | 0.65 | NPC1 (0.37) | MAPTKDM4EALDH1A1RAB9AALOX5 | |
| SCHEMBL23204805 | 0.61 | KDM4E (0.41) | MAPTKDM4EALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571031-A2 | Process for the preparation of savoury flavours | QUEST INTERNATIONAL B.V. (NL) | 1993-11-24 | — | — | EP | disclosed |