Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466474 | 0.86 | LMNA (0.60) | HDAC6GMNNALDH1A1LMNACYP2D6 | |
| SCHEMBL8573535 | 0.85 | CYP4A11 (0.47) | CYP4A11CYP4F2EPHX2ADRB2ADRB1 | |
| SCHEMBL8575084 | 0.85 | CYP4A11 (0.47) | CYP4A11CYP4F2EPHX2ADRB2ADRB1 | |
| SCHEMBL7472261 | 0.84 | CYP4F2 (0.62) | CYP4A11CYP4F2ALDH1A1LMNAMAPT | |
| SCHEMBL3679325 | 0.81 | CYP4A11 (0.72) | CYP4A11CYP4F2ALDH1A1LMNAMAPT | |
| SCHEMBL22922181 | 0.81 | CYP4F2 (0.59) | CYP4A11CYP4F2ALDH1A1LMNAMAPT | |
| SCHEMBL14733281 | 0.80 | CYP4F2 (0.49) | CYP4A11CYP4F2ALDH1A1LMNAMAPT | |
| SCHEMBL8142192 | 0.80 | ALDH1A1 (0.50) | CYP4A11CYP4F2HDAC6ALDH1A1MAPT | |
| SCHEMBL11750668 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3679362 | 0.78 | CYP4A11 (0.64) | CYP4A11CYP4F2TSHREPHX2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5852011-A | Benzimidazole derivatives | MITSUI CHEMICALS, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |